Sledzieski, Zhang, Mandoiu, Bansal. TreeFix-TP: Phylogenetic Error-Correction for Infectious Disease Transmission Network Inference. Under review.
- M.S. and Ph.D in Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 2024 (expected)
- B.S. in Computer Science, University of Connecticut, 2019
- Minor in Molecular and Cell Biology
January 2017 - May 2019
- Computational Biology Lab, University of Connecticut, Storrs, CT
- Advisor: Dr. Mukul Bansal
- Developed algorithms and software for finding optimal viral transmission history
- Developed a testing pipeline for the software using simulated viral genomic data.
Presented at IEEE ICCABS 2018 and RECOMB 2019: “TreeFix-VP: Phylogenetic Error Correction for Accurate Reconstruction of Viral Transmission Networks”
- Spring 2017: Independent study working to reconstruct full ancestral genomes using modern computational biology software and to develop a procedure for differentiating between addition and replacement lateral gene transfer events in bacteria.
October 2015 - December 2016
- Nelson Lab, University of Connecticut, Storrs, CT
- Advisor: Dr. Craig Nelson
- Developed proficiency in basic laboratory techniques and modern single cell and stem cell biology techniques, including cell culture of mouse embryonic fibroblasts and fluorescent microscopy.
- Assisted with research including analysis of single cell gene expression, embryonic stem cell development, and reprogramming of induced pluripotent stem cells.
Conference workshop talk at ICCABS Workshop on Computational Advances for Next Generation Sequencing (CANGS), Las Vegas, NV
Poster session at RECOMB, Washington, DC
Summer Research Program
May 2019 - August 2019
- Advanced Systems and Lasercom Group, MIT Lincoln Laboratory, Lexington, MA
- Developed of a test bed for automatic calibration of high speed infrared cameras under multiple focal plane array settings
- Implemented a large hardware and software system to automatically collect calibration data and perform optical power calculations
- Calibration enables the use of cameras to measure optical power emitted by a lasercom terminal
Senior Design Project
August 2019 - May 2019
- Jackson Laboratory, Farmington, CT
- Designed and developed a web interface for a CNV-calling tool developed by the Jackson Laboratory
- Designed for use by research scientists and in-hospital physicians
Technology Development Program
June 2017 - August 2017
- Optum Technology, Boston, MA
- Worked on exploratory project into the viability of machine learning as a tool to assist automatic claim adjudication and error resolution.
- Developed a machine learning facilitation pipeline which was distributed throughout Optum as a resource for other teams seeking to take advantage of machine learning.
- Worked with a suite of data science and big data tools, including scikit-learn, pandas, R, and Apache Hive.
- Placed third in the Machine Learning category of the UHG Global Hackathon.
- Computer Science
- Computational Genomics
- Computational Geometry
- Computational Problems in Evolutionary Genomics
- Machine Learning
- Software Engineering
- Machine Learning in Genomics
- Math & Statistics
- Statistical Methods
- Linear Algebra
- Multivariable Calculus
- Biology and Chemistry
- Cell Biology
- Organic Chemistry
- Association for Computing Machinery (ACM)
- Institute of Electronics Engineers (IEEE)
- Eta Kappa Nu (HKN)
- Tau Beta Pi (TBP)
- Upsilon Pi Epsilon (UPE)